Searchable abstracts of presentations at key conferences in endocrinology

ea0020p61 | Thyroid | ECE2009

Influence of pentoxifylline on peripheral blood mononuclear cells proliferation and apoptosis in Graves’ ophthalmopathy

Melnik Irina , Hlazkova Anastasiya , Kosmacheva Svetlana , Goncharova Natallia , Danilova Larisa , Romanovskiy Aleksey

Pentoxifylline (PTX), a phosphodiesterase inhibitor, has a positive therapeutic effect in some autoimmune diseases due to immunomodulatory action.The aim of the study was to assess the influence of PTX on apoptosis and peripheral blood mononuclear cells (PBMC) proliferation in patients with GravesÂ’ ophthalmopathy (GO).Twenty-four patients with GO and 32 healthy controls were investigated. GO patients were divided into two grou...